Quiz masters Joep van Deudekom, Rob Urgert, Niels van der Laan and Jeroen Woe put a famous Dutchman to the test every week with topical questions, satirical weekly reviews and musical parodies. As always, the candidate is assisted by host Paul de Leeuw. De Kwis is written by the quiz masters, together with writer Edo Schoonbeek and editor-in-chief Hans Riemens.

During 10 seasons, the program has won several awards. In 2014, for example, it won the TV statue for best new format. Two years later, the Kwismen cashed in the nomination for TV statue in the category best entertainment. De Kwis was also nominated for the Zilveren Nipkowschijf (2014) and named by Comedy Central as funniest program of the year (2014 and 2015).